Sweet's Syndrome is an acute febrile neutrophilic dermatosis. Although
it frequently appears as an idiopathic disorder, it may occur in asso
ciation, often as presenting sign, with malignancy or more rarely with
infections. We report two cases of Sweet's syndrome preceded by diges
tive infection due to Yersinia enterocolitica, affirmed by significant
rises in serum antibody titers. Other nongastrointestinal manifestati
ons of such infections are known, predominantely arthritis and erythem
a nodosum. Sweet's syndrome in a rare complication of these infections
. Treatment with systemic steroids, usually effective, can be replaced
by antibiotics with apparently favorable results. The search of an in
fectious origin should be systematic in cases of Sweet's syndrome that
appear to be idiopathic.