NASOPHARYNGEAL CONIDIOBOLOMYCOSIS IN A HORSE

Nasopharyngeal conidiobolomycosis caused by Conidiobolus coronatus was diagnosed in a horse after endoscopic and histopathologic examination s of a biopsy specimen. The fungal lesions in the nasopharynx were sub stantially reduced in size after intralesional injection of amphoteric in B through the biopsy channel of a videoendoscope in combination wit h IV administration of sodium iodide and oral administration of potass ium iodide during a 2-month period. Endoscopy performed 15 months afte r initial examination revealed regression of the granulomatous masses in the nasopharynx and complete disappearance of the nasal masses. Two months later, clinical signs recurred, and the owner elected euthanas ia without evaluation and treatment. Nasopharyngeal conidiobolomycosis may be treated successfully with intralesional injection of amphoteri cin B in combination with administration of sodium iodide and potassiu m iodide, but there is a possibility of recrudescence of infection.