ELECTROPHILIC FLUORINATION OF A HIGHLY FUNCTIONALIZED PYRROLE

Authors
BARNES KD HU YL HUNT DA
Citation
Kd. Barnes et al., ELECTROPHILIC FLUORINATION OF A HIGHLY FUNCTIONALIZED PYRROLE, Synthetic communications, 24(12), 1994, pp. 1749-1755
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
24
Issue
12
Year of publication
1994
Pages
1749 - 1755
Database
ISI
SICI code
0039-7911(1994)24:12<1749:EFOAHF>2.0.ZU;2-N
Abstract
Bromine-lithium exchange of 3-bromo-1-(triisopropylsilyl) pyrrole 6 fo llowed by treatment with N-fluorobenzenesulfonimide gave the fluoropyr role 8. Application of this methodology to the highly functionalized p yrrole 1 afforded the fluoropyrrole 4, which was found to be inaccessi ble by other approaches.