ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-POSITIVE - CRESCENTIC GLOMERULONEPHRITIS ASSOCIATED WITH ANTITHYROID DRUG-TREATMENT

Authors
DCRUZ D CHESSER AMS LIGHTOWLER C COMER M HURST MJ BAKER LRI RAINE AEG
Citation
D. Dcruz et al., ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-POSITIVE - CRESCENTIC GLOMERULONEPHRITIS ASSOCIATED WITH ANTITHYROID DRUG-TREATMENT, British journal of rheumatology, 34(11), 1995, pp. 1090-1091
Citations number
11
Categorie Soggetti
Rheumatology
Journal title
British journal of rheumatology → ACNP
ISSN journal
02637103
Volume
34
Issue
11
Year of publication
1995
Pages
1090 - 1091
Database
ISI
SICI code
0263-7103(1995)34:11<1090:ACA-CG>2.0.ZU;2-R
Abstract
Two cases of antineutrophil cytoplasmic antibody (ANCA)-positive vascu litis following treatment with propylthiouracil and carbimazole are de scribed. Both patients had crescentic glomerulonephritis proven by ren al biopsy and responded to immunosuppressive therapy and withdrawal of the anti-thyroid drugs. Though systemic vasculitis associated with pr opylthiouracil is reported, this is the first report to our knowledge of renal biopsy-proven vasculitis associated with either of these drug s.