SYNTHESIS OF PYRAZINOPSORALEN - A PYRAZINE RING-FUSED MONOFUNCTIONAL PSORALEN DERIVATIVE

Citation
Dj. Yoo et al., SYNTHESIS OF PYRAZINOPSORALEN - A PYRAZINE RING-FUSED MONOFUNCTIONAL PSORALEN DERIVATIVE, Bulletin of the Korean Chemical Society, 16(12), 1995, pp. 1212-1218
Citations number
49
Categorie Soggetti
Chemistry
ISSN journal
02532964
Volume
16
Issue
12
Year of publication
1995
Pages
1212 - 1218
Database
ISI
SICI code
0253-2964(1995)16:12<1212:SOP-AP>2.0.ZU;2-H
Abstract
An efficient synthesis of 6,8-dioxa-1,4-diazacyclopenta[b]phenanthren- 5-one (Pyrazinopsoralen) (4) has been carried out by the Suzuki coupli ng reaction as a key step starting from 5-bromo-6-methoxybenzofuran (6 ) and methyl 2-iodo-3-pyrazinecarboxylate (8).