LIPID-PEROXIDATION IN HEPATOCELLULAR-CARCINOMA

Authors
IWAGAKI H HAMAZAKI K MATSUBARA N HIRAMATSU M ORITA K MORI A
Citation
H. Iwagaki et al., LIPID-PEROXIDATION IN HEPATOCELLULAR-CARCINOMA, Acta medica Okayama, 49(6), 1995, pp. 313-315
Citations number
11
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Acta medica Okayama → ACNP
ISSN journal
0386300X
Volume
49
Issue
6
Year of publication
1995
Pages
313 - 315
Database
ISI
SICI code
0386-300X(1995)49:6<313:LIH>2.0.ZU;2-F
Abstract
In this study, we measured free radicals and thiobarbituric acid-react ive substances (TEARS) in hepatocellular carcinoma and in non-cancerou s liver parenchyma. There was a higher concentration of free radicals in malignant tissue than in non-cancerous tissue. In contrast, the lev el of TEARS was significantly (P < 0.01) lower than non-cancerous live r parenchyma. These paradoxical results suggested that antioxidative e nzyme activity and/or inhibition of lipid peroxidation were higher in hepatocellular carcinoma.