Organotin compounds are ubiquitous contaminants in the environment. Th
e high biological activity of some compounds toward aquatic organisms
lead to deleterious impacts in aquatic ecosystems. Here, the aquatic e
cotoxicology of organotins is reviewed based on a multidisciplinary ap
proach involving environmental chemical, toxicological, and ecological
aspects. Basic results were obtained both with field and laboratory s
tudies, and some of the most important recent results and conclusions
are critically reviewed. The contamination of and fate in aquatic syst
ems is reported and linked with effects at different levels of biologi
cal organization. Major emphasis is placed on the development of a con
cept of ecotoxicology that encompasses not only effect assessment alon
e, but also integrates environmental chemistry with aquatic toxicology
. Thereby, the influence of speciation for bioavailability, basic mode
s of toxic action, and aquatic toxicity are discussed. This case study
on organotins allows to a certain extent generalizations to ecotoxico
logy in general.