A. Buczynski et al., THE ADENINE-NUCLEOTIDES CONCENTRATION IN BLOOD-PLATELETS OF PATIENTS WITH CORONARY HEART-DISEASE, Herz, Kreislauf, 26(5), 1994, pp. 152-153
In 41 patients with coronary heart disease (clinically diagnosed as st
able angina according to WHO), the concentration of adenine nucleotide
s (ATP, ADP, AMP) in blood platelets was studied and compared to value
s of healthy subjects. The level of adenine nucleotides in blood plate
lets of the CHD patients was decreased (ATP: -28.1%; ADP: -36.3%). The
se changes are probably caused by the activation of platelets and by t
he release of stored adenine nucleotides (ATP, ADP).