M. Schwab et al., HYPONATREMIA AND CEREBRAL CONVULSION DUE TO SHORT-TERM DDAVP THERAPY FOR CONTROL OF ENURESIS NOCTURNA, European journal of pediatrics, 155(1), 1996, pp. 46-48
Desmopressin (DDAVP) is frequently used in the treatment of primary is
olated enuresis nocturna if other approaches have failed. We report a
further case of hyponatraemia and cerebral convulsion due to water int
oxication after intranasal DDAVP application by a 6 year-old boy with
enuresis Conclusion Although adverse reactions in DDAVP (e.g. hyponatr
aemia) are rare, it should not be considered as the first choice treat
ment of enuresis nocturna and only be used with caution.