FIRST INTERNATIONAL WORKSHOP ON PORCINE CHROMOSOME-6

Citation
Aa. Paszek et al., FIRST INTERNATIONAL WORKSHOP ON PORCINE CHROMOSOME-6, Animal genetics, 26(6), 1995, pp. 377-386
Citations number
60
Categorie Soggetti
Genetics & Heredity","Veterinary Sciences
Journal title
ISSN journal
02689146
Volume
26
Issue
6
Year of publication
1995
Pages
377 - 386
Database
ISI
SICI code
0268-9146(1995)26:6<377:FIWOPC>2.0.ZU;2-I
Abstract
Recent advances in the use of microsatellite markers and the developme nt of comparative gene mapping techniques have made the construction o f high resolution genetic maps of livestock species possible, Framewor k and comprehensive genetic linkage maps of porcine chromosome 6 have resulted from the first international effort to integrate genetic maps from multiple laboratories, Eleven highly polymorphic genetic markers were exchanged and mapped by four independent laboratories on a total of 583 animals derived from four reference populations. The chromosom e 6 framework map consists of 10 markers ordered with high local suppo rt, The average marker interval of the framework map is 15.1 cM (sex a veraged). The framework map is 135, 175 and 109 cM in length (for sex averaged, female and male maps, respectively), The comprehensive map i ncludes a total of 48 type I and type II markers with a sex averaged i nterval of 3.5 cM and is 166, 196 and 126 cM (for sex averaged, female and male maps, respectively). Additional markers within framework map marker intervals can thus be selected from the comprehensive map for further analysis of quantitative trait loci (QTL) located on chromosom e 6. The resulting maps of swine chromosome 6 provide a valuable tool for analysing and locating QTL.