PULMONARY COMPLICATIONS OF CYSTIC-FIBROSIS IN ADULTS

The demographics of cystic fibrosis (CF) are continuously changing, wi th adults representing a growing percentage of the patient population, which is expected to reach 50% by the year 2000. Pulmonary complicati ons are primarily responsible for the high morbidity and mortality in this disease. Although the radiographic findings are quite specific, t he correct diagnosis may not be suggested in the adult patient because of a lack of familiarity with its pulmonary manifestations in this ag e group. High-resolution CT (HRCT) has contributed to our understandin g of the radiographic findings, especially at the level of the small a irways. The role of imaging, including chest radiography and HRCT, is discussed. Issues that remain controversial include imaging in the acu te pulmonary exacerbation, and the routine use of imaging as part of c linical scoring and in monitoring responses to new treatment modalitie s.