BACKGROUND: Open antireflux surgery is an established long-term treatm
ent for chronic gastroesophageal reflux disease. Short-term results of
laparoscopic antireflux surgery are excellent, but long-term follow-u
p is not yet available. METHODS: Twenty-four-hour ambulatory esophagea
l pH monitoring and symptom scores were collected prior to laparoscopi
c antireflux surgery and 6 weeks postoperatively. These studies were r
epeated in an unselected cohort of patients 1 to 3 years after operati
on. RESULTS: One hundred patients who were >1 year from surgery at the
time of the present study volunteered for intermediate follow-up symp
tom assessment, and 35 also completed repeat 24-hour monitoring. The m
edian interval after surgery among these volunteers was 17 months. Thi
rty-three (94%) had a normal pH study, which correlated with improveme
nts in symptom scores. One patient had an abnormal pH study but no ref
lux symptoms, and 1 patient with an abnormal study developed recurrent
symptoms of reflux after an episode of vomiting 11 months postoperati
vely. CONCLUSIONS: The intermediate-term results of laparoscopic fundo
plication suggest that long-term efficacy of this operation will be eq
uivalent to open fundoplication.