A chordoma metastatic to the skin of the nose is reported. The patient
(a 40-year-old man) had undergone excision of a sacral chordoma 16 mo
nths previously. In patients whose clinical histories are unknown, cut
aneous metastases of chordoma can be confused with mixed tumors of swe
at glands. Cytological features, including the presence of physaliphor
ous cells, and immunohistochemical coexpression of low molecular weigh
t keratins and S-100 protein are helpful features that lead to a corre
ct diagnosis.