CAPILLARY GC-MS INVESTIGATION OF THE METABOLISM AND EXCRETION OF OXABOLONE IN MAN

Authors
BARBARULO MV BUIARELLI F CIARDI M GIARRUSSO A ROSATI F CARTONI GP
Citation
Mv. Barbarulo et al., CAPILLARY GC-MS INVESTIGATION OF THE METABOLISM AND EXCRETION OF OXABOLONE IN MAN, HRC. Journal of high resolution chromatography, 18(11), 1995, pp. 705-708
Citations number
9
Categorie Soggetti
Chemistry Analytical
Journal title
HRC. Journal of high resolution chromatography → ACNP
ISSN journal
09356304
Volume
18
Issue
11
Year of publication
1995
Pages
705 - 708
Database
ISI
SICI code
0935-6304(1995)18:11<705:CGIOTM>2.0.ZU;2-I
Abstract
The metabolism of oxabolone cipionate, yclopentyl-1-oxopropoxy)-4-hydr oxyestr-4-en-3-one, a synthetic anabolic steroid, was investigated in man, the cumulative urinary excretion and the metabolism of the compou nds being studied by GC-MS in both electron impact and chemical ioniza tion modes, After administration by injection to volunteers, five diff erent metabolites were detected in urine, The metabolites and the pare nt compound were detected in urine up to a week after administration.