PHEOHYPHOMYCOSIS CAUSED BY ALTERNARIA SPECIES AND PHAEOSCLERA DEMATIOIDES SIGLER, TSUNEDA AND CARMICHAEL

A case of phaeohyphomycosis caused by strains of both Alternaria spp. and Phaeosclera dematioides is presented. First clinical signs of myco sis appeared on the patient's face, after an injury with a straw stalk during the wheat harvest in Germany in 1942. Further signs developed in 1955 at one forearm, and again in 1968 in the mouth, leading to per foration of the palate. After treatment with amphotericin B (1973-75) she went into a 13-year-long, clinically asymptomatic remission. She r elapsed in 1988, when eight foci of the disease developed, mostly on b oth forearms. Diabetes mellitus and asthma developed at this time. Aft er pulse therapy with itraconazole the patient remains in a good clini cal condition.