GENETIC EPIDEMIOLOGY OF THE MITSUDA REACTION IN LEPROSY

Authors
FEITOSA M KRIEGER H BORECKI I BEIGUELMAN B RAO DC
Citation
M. Feitosa et al., GENETIC EPIDEMIOLOGY OF THE MITSUDA REACTION IN LEPROSY, Human heredity, 46(1), 1996, pp. 32-35
Citations number
23
Categorie Soggetti
Genetics & Heredity
Journal title
Human heredity → ACNP
ISSN journal
00015652
Volume
46
Issue
1
Year of publication
1996
Pages
32 - 35
Database
ISI
SICI code
0001-5652(1996)46:1<32:GEOTMR>2.0.ZU;2-8
Abstract
This study comprised 544 nuclear families with 2,935 individuals teste d for the Mitsuda reaction, from the Campinas region in Brazil. Segreg ation analyses suggest the segregation of a major gene (chi(1)(2) = 0. 07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelia n transmission and by rejecting the hypothesis of nontransmission of a major gene (chi(3)(2) = 0.07 - 0.0 = 0.07, p > 0.99; chi(2)(2) = 198. 28 - 0.0 = 198.28, p < 0.0001).