AIRWAY REACTIVITY OF NOSE AND BRONCHI IN PATIENTS WITH NASAL POLYPS

The aim of the study was to determine whether patients with nasal poly ps have a hyperreactive nasal mucosa and/or bronchi and whether there is any correlation between nasal and bronchial hyperreactivity. Twenty -six healthy volunteers and 10 consecutive patients with nasal polyps participated in the study. They were challenged with increasing concen trations of histamine. The nasal mucosa response was studied with rhin ostereometry and the bronchial response was estimated by peak flow. On e of the patients was mildly hyperreactive in the nose and 6 patients were hyperreactive in the bronchi. There was no correlation between na sal and bronchial. hyperreactivity. Patients with nasal polyps do not have a hyperreactive nasal mucosa but there seems to be a high inciden ce of bronchial hyperreactivity in patients-with nasal polyps.