Sclerosing encapsulating peritonitis (SEP), idiopathic or secondary, i
s a form of intraperitoneal fibrosclerosis that causes intestinal obst
ruction. In the case of a 41-year-old man with dialysis-induced SEP pr
esented here, we show that intraperitoneal hemorrhage may play an impo
rtant pathogenetic role and that the process may develop in less than
or equal to 12 weeks. Regardless of cause, the treatment of obstructio
n is operative, with dissection of the encasing membrane from the inte
stine and separation of adherent loops of small bowel until they are l
aid free and returned to their normal configuration. The prognosis aft
er appropriate operative therapy is good but depends on coexisting dis
eases.