Patients undergoing neodymium:yttrium-aluminum-garnet (Nd:YAG) laser p
osterior capsulotomy for posterior capsular opacification after penetr
ating keratoplasty were reviewed retrospectively for incidence of graf
t rejection. All patients underwent extracapsular cataract extraction
with posterior chamber intraocular lens implantation (PC-IOL) performe
d as a separate or combined procedure. Only one of 20 eyes (4.7%) of 2
0 patients developed corneal graft rejection over a follow-up period o
f 6 months to 6 years after capsulotomy. Nd:YAG laser capsulotomy does
not appear to increase the risk of corneal graft rejection.