PARANEOPLASTIC ENCEPHALOMYELITIS IN A CHILD WITH NEUROBLASTOMA

We present the case of a 12-year-old boy who developed progressive lim bic dysfunction associated with a posterior cord syndrome in conjuncti on with complex partial seizures and intrathecal synthesis of IgG. Alt hough the cerebral CT scan appeared normal, MR imaging showed signal a bnormalities in both temporal lobes. As these clinical features remind ed us of the well-known paraneoplastic encephalomyelitis (PNEM) in adu lts, we looked for a tumour and found a pelvic neuroblastoma. The diag nosis of PNEM was supported by the discovery of the antibody anti-HU i n the serum of our patient.