Oscillating pressure inflations may minimize trauma to the coronary ar
tery during coronary angioplasty. We measured in vitro diameters of po
lyolefin copolymer compliant angioplasty balloons (as a surrogate for
pressure) during pressure oscillation at the inflater to determine if
pressure oscillations at the inflater were conducted to the balloon. B
alloon diameter oscillation increased as cycle length and inflater pre
ssure amplitude increased, Currently practiced oscillating inflation (
cycle length 2-3 sec, amplitude 2-3 atm) did not effectively transmit
oscillation to the balloon. Clinically feasible optimal balloon oscill
ation was achieved at a cycle length of 6 sec and pressure amplitude o
f about 3 atm. (C) 1996 Wiley-Liss, Inc.