THE COMPARATIVE CLASTOGENIC ACTIVITY OF MAINSTREAM TOBACCO-SMOKE FROMCIGARETTES WIDELY CONSUMED IN ARMENIA

Authors
NERSESSIAN AK ARUTYUNYAN RM
Citation
Ak. Nersessian et Rm. Arutyunyan, THE COMPARATIVE CLASTOGENIC ACTIVITY OF MAINSTREAM TOBACCO-SMOKE FROMCIGARETTES WIDELY CONSUMED IN ARMENIA, MUTATION RESEARCH, 321(1-2), 1994, pp. 89-92
Citations number
11
Categorie Soggetti
Genetics & Heredity",Toxicology
Journal title
MUTATION RESEARCH → ACNP
ISSN journal
00275107
Volume
321
Issue
1-2
Year of publication
1994
Pages
89 - 92
Database
ISI
SICI code
0027-5107(1994)321:1-2<89:TCCAOM>2.0.ZU;2-F
Abstract
Whole-body exposure of male albino Swiss mice to the mainstream smoke produced by 10 types of cigarettes widely consumed in Armenia resulted in a significant increase (2.4-5.6-fold) of the number of micronuclea ted bone marrow polychromatic erythrocytes. The smoke produced by ciga rettes manufactured in Armenia, Russia and Bulgaria was more clastogen ic than the smoke produced by cigarettes manufactured in the USA. A hi gh direct correlation was observed between the number of micronucleate d polychromatic erythrocytes and the content of tar and nicotine.