Ak. Nersessian et Rm. Arutyunyan, THE COMPARATIVE CLASTOGENIC ACTIVITY OF MAINSTREAM TOBACCO-SMOKE FROMCIGARETTES WIDELY CONSUMED IN ARMENIA, MUTATION RESEARCH, 321(1-2), 1994, pp. 89-92
Whole-body exposure of male albino Swiss mice to the mainstream smoke
produced by 10 types of cigarettes widely consumed in Armenia resulted
in a significant increase (2.4-5.6-fold) of the number of micronuclea
ted bone marrow polychromatic erythrocytes. The smoke produced by ciga
rettes manufactured in Armenia, Russia and Bulgaria was more clastogen
ic than the smoke produced by cigarettes manufactured in the USA. A hi
gh direct correlation was observed between the number of micronucleate
d polychromatic erythrocytes and the content of tar and nicotine.