ENGINEERING PROTEINS TO FACILITATE BIOPROCESSING

Authors
NYGREN PA STAHL S UHLEN M
Citation
Pa. Nygren et al., ENGINEERING PROTEINS TO FACILITATE BIOPROCESSING, Trends in biotechnology, 12(5), 1994, pp. 184-188
Citations number
47
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Trends in biotechnology → ACNP
ISSN journal
01677799
Volume
12
Issue
5
Year of publication
1994
Pages
184 - 188
Database
ISI
SICI code
0167-7799(1994)12:5<184:EPTFB>2.0.ZU;2-E
Abstract
Genetic engineering is now being applied to aid the purification of re combinant proteins. The addition of specifically designed tags or the modification of sequences within the target-gene product has enabled t he development of novel strategies for downstream processing that can be employed for efficient recovery of both native or modified proteins . This article discusses novel trends in genetic engineering that aid the bioprocessing of recombinant proteins,