Although both continuous haemofiltration and continuous haemodialysis
are techniques routinely employed in the management of critically ill
patients, deciding on a drug dosing regimen is often difficult. This a
rticle highlights the factors influencing drug removal by both process
es, the difficulties associated with the interpretation of research in
this area and offers a number of approaches which can be used when se
lecting a dosing regimen for a patient receiving one of these therapie
s.