Ja. Jansen et al., HISTOLOGIC EVALUATION OF THE SOFT-TISSUE RESPONSE TO SINTERED AUSTENITIC STAINLESS-STEEL FIBER STRUCTURES, Journal of materials science. Materials in medicine, 5(5), 1994, pp. 284-290
Recently it has been supposed that the soft tissue response to fibre m
esh materials can be influenced by changing the flexibility and/or por
osity of these materials. Therefore, to test this hypothesis, small si
ntered stainless steel (316L) fibre web implants with varying flexibil
ities and porosities were inserted subcutaneously into the dorsum of r
abbits. The implants were left in situ for 15 weeks. Histological and
tissue compatibility evaluations were performed. It was found that the
best tissue reaction developed around the most porous fibre web mater
ial. Nevertheless, because of the possible occurrence of corrosion phe
nomena, the real existence of a relationship between implant porosity
and connective tissue behaviour is still not clear.