Cb. Johansson et al., QUANTITATIVE COMPARISON OF SCREW-SHAPED COMMERCIALLY PURE TITANIUM AND ZIRCONIUM IMPLANTS IN RABBIT TIBIA, Journal of materials science. Materials in medicine, 5(6-7), 1994, pp. 340-344
Screw-shaped implants with an outer diameter of 3.7 mm and a total len
gth of 8 mm were made from rods of commercially pure titanium (c.p. Ti
) and commercially pure zirconium (c.p. Zr). Prior to insertion in rab
bit tibia for 12 weeks, the surface roughness of two randomly chosen c
.p. Ti and two c.p. Zr machined implants of the batch were numerically
and visually described with a TopScan 3-D system. Irrespective of imp
lant material, they demonstrated rather similar surface roughnesses, f
or example, the R(a) and R(q) values (that describe the average deviat
ion from the mean line) were 0.79 and 1.18 for c.p. Ti versus 0.56 and
0.86 for c.p. Zr. Each rabbit had four implants inserted; two made of
c.p. Ti in one leg and two made of c.p. Zr in the other. The bone tis
sue reactions to the materials were qualitatively and quantitatively e
xamined. Removal torque tests were performed on the distal implants an
d histomorphometrical evaluations of the proximal ones. No qualitative
or quantitative bone differences were observed. Removal torque measur
ements demonstrated a mean of 26.2 N cm +/- 9.6 for c.p. Ti versus a m
ean of 25.9 N cm +/- 7.1 for the c.p. Zr implants. Histomorphometrical
comparisons of the bone-to-metal contact revealed a mean of 29 +/- 10
.2% for c.p. Ti and a mean of 19 +/- 5.5% for the c.p. Zr samples. The
mean bone area in the threads around the c.p. Ti samples was 49 +/- 1
6.6% compared to 43 +/- 7.9% for the c.p. Zr group. Commercially pure
titanium and zirconium implants seemed to be well accepted by the bone
bed after 12 weeks of insertion in rabbit bone.