INTRAMEDULLARY BONE-FORMATION AFTER POLYLACTIC ACID WIRE IMPLANTATION

Authors
OTTO TE PATKA P HAARMAN HJTM KLEIN CPAT VRIESDE R
Citation
Te. Otto et al., INTRAMEDULLARY BONE-FORMATION AFTER POLYLACTIC ACID WIRE IMPLANTATION, Journal of materials science. Materials in medicine, 5(6-7), 1994, pp. 407-410
Citations number
22
Categorie Soggetti
Polymer Sciences","Medicine Miscellaneus","Materials Science, Biomaterials
Journal title
Journal of materials science. Materials in medicine → ACNP
ISSN journal
09574530
Volume
5
Issue
6-7
Year of publication
1994
Pages
407 - 410
Database
ISI
SICI code
0957-4530(1994)5:6-7<407:IBAPAW>2.0.ZU;2-#
Abstract
Semi-crystalline poly-L-lactic acid (PLLA) wire was implanted intramed ullary in rat tibiae to evaluate the fracture healing processes and th e tissue reaction or: the PLLA in a fractured bone. The fracture heali ng after PLLA implantation was compared to a sham-operated group of an imals. In all animals with intramedullary PLLA wire implantation newly formed bone was seen immediately against the implant 2 and 6 months a fter implantation. None of the sham-operated animals showed newly form ed intramedullary bone formation other than fracture heating callus an d normal trabecular bone.