The Clozapine Resource Centre in British Columbia is a centralized inf
ormation source for all physicians wishing to prescribe clozapine and
also performs back-up hematological and compliance monitoring. Laborat
ories fax weekly hematology results to physicians and to the center. T
he center enters results in a national database and compiles twice-wee
kly noncompliance reports; physicians are notified of abnormal results
, and caregivers of noncompliance. The centralized system obviates the
practice in some jurisdictions of hiring case coordinators to oversee
these procedures and may reduce physician reluctance to prescribe clo
zapine. It improves coordination among monitoring and treatment partie
s and ensures better continuity of care.