KINETIC RESOLUTION OF RACEMIC TRICARBONYL(2-CHLOROANISOLE)CHROMIUM VIA PALLADIUM-CATALYZED ASYMMETRIC ALKOXYCARBONYLATION

Authors
CARPENTIER JF PAMART L MACIEWJESKI L CASTANET Y BROCARD J MORTREUX A
Citation
Jf. Carpentier et al., KINETIC RESOLUTION OF RACEMIC TRICARBONYL(2-CHLOROANISOLE)CHROMIUM VIA PALLADIUM-CATALYZED ASYMMETRIC ALKOXYCARBONYLATION, Tetrahedron letters, 37(2), 1996, pp. 167-170
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
2
Year of publication
1996
Pages
167 - 170
Database
ISI
SICI code
0040-4039(1996)37:2<167:KRORTV>2.0.ZU;2-B
Abstract
Tricarbonyl(o-chloroanisole)chromium was treated with an alcohol and c arbon monoxide in the presence of triethylamine and a chiral palladium catalyst to give (o-methoxybenzoate ester)Cr(CO)(3) complexes in high selectivity with up to 30% ee. Starling tricarbonyl(o-chloroanisole)c hromium was recovered in up to 39% ee. The Pd/PPFA catalytic system ex hibited high reactivity and selectivity for the carbonylation reaction .