STEREOSELECTIVE SYNTHESIS OF THE C-RING AND CD-RING SYSTEMS OF HEMIBREVETOXIN-B

Authors
NAKATA T NOMURA S MATSUKURA H MORIMOTO M
Citation
T. Nakata et al., STEREOSELECTIVE SYNTHESIS OF THE C-RING AND CD-RING SYSTEMS OF HEMIBREVETOXIN-B, Tetrahedron letters, 37(2), 1996, pp. 217-220
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
2
Year of publication
1996
Pages
217 - 220
Database
ISI
SICI code
0040-4039(1996)37:2<217:SSOTCA>2.0.ZU;2-E
Abstract
The 7, 7-membered CD ring system of hemibrevetoxin B was stereoselecti vely synthesized. The crucial steps involve the Sharpless asymmetric e poxidation, cyclization to the 6-membered ether, and double rearrangem ent of the 6, 6-membered bicyclic ether with the simultaneous ring exp ansion.