Objective To determine the role of pre-operative cystoscopy in men und
ergoing radical prostatectomy for clinically localized adenocarcinoma
of the prostate.Patients and methods One hundred men undergoing radica
l prostatectomy for clinically localized adenocarcinoma of the prostat
e were evaluated for coexisting bladder pathology from a retrospective
review of their charts and records. Results Four of 100 men undergoin
g radical prostatectomy for clinically localized prostate cancer were
found to have synchronous bladder tumours, Two of these had superficia
l low-grade transitional cell carcinoma (TCC), one had a poorly differ
entiated invasive TCC and the last was found to have an inverted papil
loma during radical retropubic prostatectomy, The patient with invasiv
e disease died before the initiation of definitive therapy. The other
three men are free of disease 2 years after diagnosis and treatment. C
onclusion Because of the low cost and minimal morbidity of pre-operati
ve flexible cystoscopy, we recommend that this procedure be performed
on the operating table before prostatectomy, In patients with gross or
microscopic haematuria, a significant history of smoking, a prior his
tory of urothelial malignancy or symptoms of bladder outlet obstructio
n, cystoscopy would be best performed before surgery in an outpatient
setting.