COMORBIDITY IN OBSESSIVE-COMPULSIVE DISORDER - FOCUS ON DEPRESSION

The authors investigated the comorbidity between obsessive-compulsive disorder (OCD) and other psychiatric disorders in a group of 154 outpa tients. The influence of an associate major depressive disorder (MDD) on the outcome of treatment with clomipramine was examined in a subgro up of 52 patients. The results showed that MDD was the most frequent d isorder associated with OCD (almost 20% of the patients), followed by generalized anxiety and panic disorder. The co-presence of depression delayed the effect of clomipramine.