Cpat. Klein et al., CORTICAL BONE INGROWTH IN GROOVED IMPLANTS WITH CALCIUM-PHOSPHATE COATINGS - A GAP MODEL STUDY, Journal of materials science. Materials in medicine, 5(9-10), 1994, pp. 569-574
In in vivo experiments the gap healing of uncoated grooves and grooves
coated with HA, HAH (heat treated hydroxylapatite) and FA was studied
histologically and histometrically. Cylinders with grooves (0.25 mm,
0.50 mm, 0.75 mm or 1.0 mm depth) were implanted in cortical bone of g
oats for 3, 6 or 12 weeks. In the uncoated gaps after 3 weeks of impla
ntation no bone ingrowth could be observed. Afer 6 weeks of implantati
on about 35% bone ingrowth was seen in the uncoated gap independent of
gap depth. There was mostly no bone contact with the titanium surface
. the presence of a coating enhanced bone ingrowth and initiated more
bone contact. After 3 weeks of implantation there was more bone ingrow
th and after 6 weeks the bone ingrowth and bone contact was increased,
independent of the coating type. HAH showed the highest bone ingrowth
. The bone ingrowth started from the periphery of the host bone.