CHARACTERIZATION OF GROWTH AND ELECTRICAL-ACTIVITY OF NERVE-CELLS CULTURED ON MICROELECTRONIC SUBSTRATES - TOWARDS HYBRID NEURO-ELECTRONIC DEVICES

Authors
BOVE M GRATTAROLA M TEDESCO M VERRESCHI G
Citation
M. Bove et al., CHARACTERIZATION OF GROWTH AND ELECTRICAL-ACTIVITY OF NERVE-CELLS CULTURED ON MICROELECTRONIC SUBSTRATES - TOWARDS HYBRID NEURO-ELECTRONIC DEVICES, Journal of materials science. Materials in medicine, 5(9-10), 1994, pp. 684-687
Citations number
13
Categorie Soggetti
Polymer Sciences","Medicine Miscellaneus","Materials Science, Biomaterials
Journal title
Journal of materials science. Materials in medicine → ACNP
ISSN journal
09574530
Volume
5
Issue
9-10
Year of publication
1994
Pages
684 - 687
Database
ISI
SICI code
0957-4530(1994)5:9-10<684:COGAEO>2.0.ZU;2-B
Abstract
The main purpose of this paper is to describe several techniques for c haracterizing the functional coupling of a population of in vitro cult ured neurons to a planar array of microtransducers. Both experimental aspects and computer simulations are considered. Experimental data inc lude a comparison of neuron growth on various substrata and multichann el extracellular monitoring of neuron activity. Simulations dealing wi th impedance measurements and extracellular stimulation are also descr ibed.