AH17, A NEW NONPOLYENIC ANTIFUNGAL ANTIBIOTIC PRODUCED BY A STRAIN OFSPIRILLOSPORA

Authors
HACENE H LEFEBVRE G
Citation
H. Hacene et G. Lefebvre, AH17, A NEW NONPOLYENIC ANTIFUNGAL ANTIBIOTIC PRODUCED BY A STRAIN OFSPIRILLOSPORA, Microbios, 83(336), 1995, pp. 199-205
Citations number
12
Categorie Soggetti
Microbiology
Journal title
Microbios → ACNP
ISSN journal
00262633
Volume
83
Issue
336
Year of publication
1995
Pages
199 - 205
Database
ISI
SICI code
0026-2633(1995)83:336<199:AANNAA>2.0.ZU;2-B
Abstract
An antibiotic (AH17) was produced by Spirillospora strain 719. This su bstance was obtained only from the broth filtrate after precipitation with acetic acid followed by extraction with n-butanol. Its purificati on was carried out by thin layer chromatography on silica gel followed by HPLC procedures. It showed activity against Gram-positive and Gram -negative bacteria and fungi. The spectroscopic and chemical propertie s were examined and indicated that AH17 was a quinone. It seems that t his is a new antibiotic from Spirillospora.