AGE-RELATED-CHANGES OF HISTOLOGICAL COMPOSITION IN ESTABLISHED BENIGNPROSTATIC HYPERPLASIA

To clarify the effect of aging on the histological composition of esta blished benign prostatic hyperplasia (BPH), quantitative morphometric analyses were performed. Specimens were obtained from 23 patients who underwent transurethral resection of the prostate due to symptomatic B PH. Smooth muscle cells, fibrous tissue, glandular cells, glandular lu men and vascular tissue were quantified. Stromal and glandular compone nts of established BPH did not correlate with age, whereas the proport ion of vascular tissue was inversely correlated with age (r = -0.572, p = 0.0046). In the present series, the main characteristic of BPH tis sue of elderly men appeared to be decreased vascularity.