B. Kuschel et E. Estey, ISOLATED LEUKEMIA-CUTIS AND CNS INVOLVEMENT IN COMBINATION WITH CYTOGENETIC FINDINGS OF TRISOMY-8 - 2 CASE-REPORTS, Leukemia & lymphoma, 20(1-2), 1995, pp. 153-155
We describe two patients who showed a very similar, but atypical cours
e of acute myelogenous leukemia. They demonstrated skin nodules, spina
l fluid and CNS involvement whereas bone marrow and blood remained cle
ar. Nonetheless both had cytogenetic findings of trisomy 8 in the marr
ow and were resistant to a combination of cytarabine, idarubicin, flud
arabine, and granulocyte-colony stimulating factor.