A 56-year-old woman presented with CML in lymphoid blast crisis. Compl
ete remission with no suggestion of CML was achieved with chemotherapy
. Twenty-six months later, an isolated ocular anterior chamber relapse
of acute leukemia presenting as uveitis (ocular masquerade syndrome)
was diagnosed and treated with radiotherapy. Ten months later, a secon
d ocular relapse in the same location was diagnosed and treated with r
adiotherapy. Two months later, a systemic relapse into second chronic
phase was diagnosed and is currently being treated with alpha interfer
on. Only one previous case of leukemic hypopyon in CML has been report
ed. This is also the first case of isolated ocular blast crisis relaps
e in CML to be described.