COMPLEX IGA GAMMOPATHY IN GAUCHERS-DISEASE

Citation
L. Shvidel et al., COMPLEX IGA GAMMOPATHY IN GAUCHERS-DISEASE, Leukemia & lymphoma, 20(1-2), 1995, pp. 165-168
Citations number
12
Categorie Soggetti
Hematology
Journal title
ISSN journal
10428194
Volume
20
Issue
1-2
Year of publication
1995
Pages
165 - 168
Database
ISI
SICI code
1042-8194(1995)20:1-2<165:CIGIG>2.0.ZU;2-P
Abstract
A 55-year-old Jewish patient was simultaneously diagnosed as having Ga ucher's disease and IgA multiple myeloma. Serum protein electrophoresi s and immunoelectrophoresis showed two different IgA kappa type monocl onal spikes. After four years of observation, a rapid fatal course of disease developed together with expression of J chain protein and an a dditional IgA lambda paraprotein. Although dysproteinaemias and multip le myeloma have occasionally been reported in Gaucher's patients, such a complex gammopathy has to the best of our knowledge not yet been de scribed.