Sj. Coniglio et Rd. Stevenson, GROWTH-HORMONE DEFICIENCY IN 2 CHILDREN WITH CEREBRAL-PALSY, Developmental Medicine and Child Neurology, 37(11), 1995, pp. 1013-1015
The authors describe two children with cerebral palsy and linear growt
h failure secondary to growth hormone deficiency. One of the children
was successfully treated with growth hormone replacement therapy. His
linear growth velocity increased from 3cm/year before therapy to 8.3cm
/year during the first two years of therapy. Potential complications s
uch as worsening orthopedic status did not occur. Psychosocial benefit
s were noted. The authors conclude that growth hormone deficiency may
play a role in linear growth failure in some children with cerebral pa
lsy and that some of these children may benefit from growth hormone th
erapy.