INFLUENCE OF INJECTION SITE ON THE ABSORPTION OF BENZYLPENICILLIN SODIUM IN THE DROMEDARY

Benzylpenicillin absorption was compared in four dromedaries following injection subcutaneously and at three different intramuscular sites ( neck, semitendinous and gluteal muscles). The rate of absorption (t(1/ 2ab) and T-max) was slower after subcutaneous compared to intramuscula r injection, but the extent of absorption (AUG) was similar for both r outes of administration. Following intramuscular injection, the data s uggest that the extent of absorption was highest from the semitendinou s site and lowest in the neck site. These results were discussed and c ompared to those reported in other species.