CONGENITAL DYSTROPHY-LIKE MYOPATHY IN A BRITTANY SPANIEL PUPPY

A congenital myopathy is reported in the only male puppy from a litter of Brittany Spaniels. The condition was manifested clinically as gene ralized weakness, mild generalized muscle atrophy and difficulty in ea ting due to tongue muscle hypertrophy. Creatine kinase values were ext remely high. Electromyographically, there were complex repetitive disc harges that persisted (pseudomyotonia). Histopathologic examination re vealed muscle fiber degeneration, size variation, hyalinization, miner alization, necrosis, and regeneration. Clinical signs, serum biochemis try, electrophysiological and pathological findings of this myopathy h ave much in common with the canine X-linked muscular dystrophies and w ith Duchenne muscular dystrophy in humans.