Using three fluorinated steroids as examples, it is demonstrated that
for simple multi-fluorinated organic molecules single-pulse and cross-
polarization magic-angle spinning experiments with proton decoupling a
re both feasible and informative. Spinning sideband manifolds are used
to obtain shielding tensor components, and shielding tensor informati
on is also obtained from static lineshape analysis, Dipolar dephasing
and rotational resonance effects are illustrated, and fluorine spin-la
ttice relaxation times have been measured, Spin-diffusion effects are
demonstrated for one compound via 2-D spin-exchange experiments, In ad
dition, one compound is shown to exhibit polymerphism, Fluorine-19 sol
ution-state NMR spectral information is also presented, for comparison
with the accrued solid-state NMR data.