CEREBRAL METASTASES IN UROTHELIAL CARCINO MA

The treatment results of 6 patients with solitary brain metastases fro m bladder cancer were evaluated. Three underwent surgery plus radiothe rapy, three whole-brain irradiation alone. Prognostic factors of opera ted patients were more favourable. Two of them survived for more than 2 years. All other patients had extracranial metastases and survived a t most 4 months. In 2/3 cases brain metastases showed no regression af ter irradiation alone (survival: 1.5 months), in the third case a comp lete remission was observed (survival: 4 months). An effective local c ontrol gives some selected patients a chance to profit from a favourab le course of the disease.