THE PATHOLOGY OF HEPATITIS-C

Inpatients with C virus, liver biopsy is an essential examination for diagnosis of chronic hepatitis. This examination evaluates the two bas ic lesions of the disease: aggressivity and fibrosis. During antiviral treatment, only liver biopsy is able to give precise details about li ver lesions and no reliable serum test is yet available for the follow -up. Molecular biology methods applied to liver sections for viral gen ome detection will be of great interest for follow up and pathophysiol ogy of the chronic disease. These sensitive techniques will supply abs ence of any pathognomonic histological feature associated with C virus in liver tissue.