Wjg. Oyen et al., NUCLEAR ARTHROGRAPHY - COMBINED SCINTIGRAPHIC AND RADIOGRAPHIC PROCEDURE FOR DIAGNOSIS OF TOTAL HIP-PROSTHESIS LOOSENING, The Journal of nuclear medicine, 37(1), 1996, pp. 62-70
Radiographic arthrography and bone scintigraphy are common diagnostic
procedures used for evaluating total hip prostheses. In this study, bo
th techniques are combined, and nuclear contrast imaging (nuclear arth
rography) is added, The efficacy of the procedures is evaluated. Metho
ds: After intravenous injection of Tc-99m-methylene diphosphonate (MDP
), standard radiographic arthrography was performed in 105 patients (1
07 prostheses). The radiographic contrast medium was mixed with insolu
ble In-111-colloid (5 MBq/20 mi). After completion of the radiographic
arthrography, nuclear arthrography was performed, and multiple-view d
ual-isotope images (In-111, 247-keV peak only) were recorded. Images w
ere interpreted by superposition of the In-111 image and the correspon
ding Tc-99m-MDP image, the latter serving as a landmark for the positi
on of the prosthesis and osseous structures. Findings at surgery were
used as the gold standard. Results: In both cemented and uncemented ac
etabular and femoral components, nuclear arthrography performed better
than or equal to radiographic arthrography (70%-90% and 60%-75%, resp
ectively). Nuclear arthrography had higher diagnostic accuracy than Tc
-99m-MDP images alone. Conclusion: Nuclear arthrography is a sensitive
technique for detection of loosening of prostheses, offering added va
lue over radiographic arthrography and bone scanning alone, especially
for evaluation of the femoral component. Radiographic arthrography re
mains necessary not only for adequate deposition of contrast agents bu
t also for detailed evaluation of osseous structures.