Technetium-99m-HMPAO interictal SPECT was performed on three pediatric
patients with Sturge-Weber syndrome (SWS). Results: Brain SPECT of al
l three patients demonstrated markedly diminished tracer localization
in the affected hemisphere. In one patient, the SPECT abnormality was
more extensive than the associated abnormalities on CT and MRI. Conclu
sion: Technetium-99m-HMPAO brain SPECT can detect cerebral perfusion a
bnormalities associated with SWS and deserves consideration in the ima
ging evaluation of SWS patients.