POLYIONS FOR BIOCOMPATIBLE MATERIALS

Starting from the thermodynamic properties of some polyamidoamines, sh owing a protonation behaviour similar to that of small molecules, a re lationship with the ability to form polymer-polymer complexes with hep arin or heparin-like macromolecules was found. In the light of these r esults, new heparinisable materials (PUPA and EVAPA) were synthesised, and the surface and bulk structures were understood on the basis of t he enhanced hydrophilic characters when these materials are protonated at physiological pH.