THE SUBCELLULAR-LOCALIZATION OF 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-4 AND ITS INTERACTION WITH ACTIN

Authors
MARKUS M HUSEN B ADAMSKI J
Citation
M. Markus et al., THE SUBCELLULAR-LOCALIZATION OF 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-4 AND ITS INTERACTION WITH ACTIN, Journal of steroid biochemistry and molecular biology, 55(5-6), 1995, pp. 617-621
Citations number
19
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Journal of steroid biochemistry and molecular biology → ACNP
ISSN journal
09600760
Volume
55
Issue
5-6
Year of publication
1995
Pages
617 - 621
Database
ISI
SICI code
0960-0760(1995)55:5-6<617:TSO1DT>2.0.ZU;2-4
Abstract
The porcine 17 beta-hydroxysteroid dehydrogenase type 4 is the key enz yme for the inactivation of estradiol. Its localization in peroxisomes was proven by immunogold electron microscopy. Interactions of the 17 beta-hydroxysteroid dehydrogenase with cytoskeletal proteins might be mandatory for a topical assignment of enzymatic activity to defined su bcellular compartments.