CHRONOBIOLOGICAL ASPECTS OF PULMONARY THROMBOEMBOLISM

A growing body of evidence has recently accumulated suggesting that se veral unfavorable cardiovascular events, e.g., myocardial angina and i nfarction, sudden cardiac death, and stroke, present a specific tempor al pattern in their occurrence, This has also been shown to be true fo r fatal pulmonary thromboembolism, with a high frequence peak in winte r and in the morning hours. The authors report the circannual and circ adian aspects of pulmonary thromboembolism, analysing both the tempora l patterns of the underlying favouring or precipitating factors, and t he possible therapeutic implications.